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Anatomy & Neurobiology | Washington University in St. Louis

Our laboratory develops and uses computerized brain mapping techniques to study the structure, function, and development of cerebral cortex in humans and nonhuman primates.

Cortical Cortography

  • Caret software for visualizing and analyzing experimental data on surfaces and volumes
  • The SumsDB database of published (freely available) and unpublished (private) neuroimaging data
  • Webcaret software for online visualization of SumsDB datasets
  • Atlases of human, macaque, mouse, and rat that facilitate cross-study comparisons and data mining
  • Neuroimaging foci. [link = xxx] Published stereotaxic coordinates (‘foci’) are especially amenable to data mining. SumsDB currently provides free access to 31,000 foci from 1,000 studies.

Ongoing Research Projects

Human Cortical Development In collaboration with Terrie Inder, Jeff Neil, Jason Hill, and others, we study human cortical development in prematurely born infants. Our objectives are to better understand normal cortical maturation and to characterize cortical abnormalities that correlate with abnormal childhood development.

Cortical Structure and Function in Disease. We use surface-based approaches to characterize abnormalities in cortical structure and function in a variety of disease conditions, including autism, schizophrenia, and Williams Syndrome.

Interspecies Comparisons. We use interspecies surface-based registration to compare cortical organization in macaques, humans, and great apes.

The Neuroscience Information Framework (NIF) [1] is a collaborative effort, funded by the NIH Blueprint, to provide a ‘one-stop shopping’ portal for a wide variety of neuroscience resources.

Personal tools
Sums Database